🗊Презентация Autonomic Nervous System

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Слайд 1


Autonomic Nervous System Overview Anatomy Physiology
Описание слайда:
Autonomic Nervous System Overview Anatomy Physiology

Слайд 2


The Autonomic Nervous System Regulate activity of smooth muscle, cardiac muscle & certain glands Structures involved general visceral afferent neurons general visceral efferent neurons integration center within the brain Receives input from limbic system and other regions of the cerebrum
Описание слайда:
The Autonomic Nervous System Regulate activity of smooth muscle, cardiac muscle & certain glands Structures involved general visceral afferent neurons general visceral efferent neurons integration center within the brain Receives input from limbic system and other regions of the cerebrum

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Autonomic versus Somatic NS Somatic nervous system consciously perceived sensations excitation of skeletal muscle one neuron connects CNS to organ Autonomic nervous system unconsciously perceived visceral sensations involuntary inhibition or excitation of smooth muscle, cardiac muscle or glandular secretion two neurons needed to connect CNS to organ preganglionic and postganglionic neurons
Описание слайда:
Autonomic versus Somatic NS Somatic nervous system consciously perceived sensations excitation of skeletal muscle one neuron connects CNS to organ Autonomic nervous system unconsciously perceived visceral sensations involuntary inhibition or excitation of smooth muscle, cardiac muscle or glandular secretion two neurons needed to connect CNS to organ preganglionic and postganglionic neurons

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Autonomic versus Somatic NS Autonomic NS pathway is a 2 neuron pathway Somatic NS pathway only contains one neuron.
Описание слайда:
Autonomic versus Somatic NS Autonomic NS pathway is a 2 neuron pathway Somatic NS pathway only contains one neuron.

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Basic Anatomy of ANS Preganglionic neuron cell body in brain or spinal cord axon is myelinated type B fiber that extends to autonomic ganglion Postganglionic neuron cell body lies outside the CNS in an autonomic ganglion axon is unmyelinated type C fiber that terminates in a visceral effector
Описание слайда:
Basic Anatomy of ANS Preganglionic neuron cell body in brain or spinal cord axon is myelinated type B fiber that extends to autonomic ganglion Postganglionic neuron cell body lies outside the CNS in an autonomic ganglion axon is unmyelinated type C fiber that terminates in a visceral effector

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Divisions of the ANS 2 major divisions parasympathetic sympathetic Dual innervation one speeds up organ one slows down organ Sympathetic NS increases heart rate Parasympathetic NS decreases heart rate
Описание слайда:
Divisions of the ANS 2 major divisions parasympathetic sympathetic Dual innervation one speeds up organ one slows down organ Sympathetic NS increases heart rate Parasympathetic NS decreases heart rate

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Autonomic Nervous System Overview Anatomy Neurotransmitter Physiology
Описание слайда:
Autonomic Nervous System Overview Anatomy Neurotransmitter Physiology

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Sources of Dual Innervation Sympathetic (thoracolumbar) division preganglionic cell bodies in thoracic and first 2 lumbar segments of spinal cord Parasympathetic (craniosacral) division preganglionic cell bodies in nuclei of 4 cranial nerves and the sacral spinal cord
Описание слайда:
Sources of Dual Innervation Sympathetic (thoracolumbar) division preganglionic cell bodies in thoracic and first 2 lumbar segments of spinal cord Parasympathetic (craniosacral) division preganglionic cell bodies in nuclei of 4 cranial nerves and the sacral spinal cord

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Locations of Autonomic Ganglia Sympathetic Ganglia trunk (chain) ganglia near vertebral bodies prevertebral ganglia near large blood vessel in gut celiac superior mesenteric inferior mesenteric Parasympathetic Ganglia terminal ganglia in wall of organ
Описание слайда:
Locations of Autonomic Ganglia Sympathetic Ganglia trunk (chain) ganglia near vertebral bodies prevertebral ganglia near large blood vessel in gut celiac superior mesenteric inferior mesenteric Parasympathetic Ganglia terminal ganglia in wall of organ

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Autonomic Plexuses Cardiac plexus Pulmonary plexus Celiac (solar) plexus Superior mesenteric Inferior mesenteric Hypogastric
Описание слайда:
Autonomic Plexuses Cardiac plexus Pulmonary plexus Celiac (solar) plexus Superior mesenteric Inferior mesenteric Hypogastric

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Structures of Sympathetic NS Preganglionic cell bodies at T1 to L2 Rami communicantes white ramus = myelinated = preganglionic fibers gray ramus = unmyelinated = postganglionic fibers Postganglionic cell bodies sympathetic chain ganglia along the spinal column prevertebral ganglia at a distance from spinal cord celiac ganglion superior mesenteric ganglion inferior mesenteric ganglion
Описание слайда:
Structures of Sympathetic NS Preganglionic cell bodies at T1 to L2 Rami communicantes white ramus = myelinated = preganglionic fibers gray ramus = unmyelinated = postganglionic fibers Postganglionic cell bodies sympathetic chain ganglia along the spinal column prevertebral ganglia at a distance from spinal cord celiac ganglion superior mesenteric ganglion inferior mesenteric ganglion

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Ganglia & Plexuses of Sympathetic NS
Описание слайда:
Ganglia & Plexuses of Sympathetic NS

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Pathways of Sympathetic Fibers Spinal nerve route out same level Sympathetic chain route up chain & out spinal n Collateral ganglion route out splanchnic n to collateral ganglion
Описание слайда:
Pathways of Sympathetic Fibers Spinal nerve route out same level Sympathetic chain route up chain & out spinal n Collateral ganglion route out splanchnic n to collateral ganglion

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Organs Innervated by Sympathetic NS Structures innervated by each spinal nerve sweat glands, arrector pili mm., blood vessels to skin & skeletal mm. Thoracic & cranial plexuses supply: heart, lungs,esophagus & thoracic blood vessels plexus around carotid artery to head structures Splanchnic nerves to prevertebral ganglia supply: GI tract from stomach to rectum, urinary & reproductive organs
Описание слайда:
Organs Innervated by Sympathetic NS Structures innervated by each spinal nerve sweat glands, arrector pili mm., blood vessels to skin & skeletal mm. Thoracic & cranial plexuses supply: heart, lungs,esophagus & thoracic blood vessels plexus around carotid artery to head structures Splanchnic nerves to prevertebral ganglia supply: GI tract from stomach to rectum, urinary & reproductive organs

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Circuitry of Sympathetic NS Divergence = each preganglionic cell synapses on many postganglionic cells Mass activation due to divergence multiple target organs fight or flight response explained Adrenal gland modified cluster of postganglionic cell bodies that release epinephrine & norepinephrine into blood
Описание слайда:
Circuitry of Sympathetic NS Divergence = each preganglionic cell synapses on many postganglionic cells Mass activation due to divergence multiple target organs fight or flight response explained Adrenal gland modified cluster of postganglionic cell bodies that release epinephrine & norepinephrine into blood

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Anatomy of Parasympathetic NS Preganglionic cell bodies found in 4 cranial nerve nuclei in brainstem S2 to S4 spinal cord Postganglionic cell bodies very near or in the wall of the target organ in a terminal ganglia
Описание слайда:
Anatomy of Parasympathetic NS Preganglionic cell bodies found in 4 cranial nerve nuclei in brainstem S2 to S4 spinal cord Postganglionic cell bodies very near or in the wall of the target organ in a terminal ganglia

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Parasympathetic Cranial Nerves Oculomotor nerve ciliary ganglion in orbit ciliary muscle & pupillary constrictor muscle inside eyeball Facial nerve pterygopalatine and submandibular ganglions supply tears, salivary & nasal secretions Glossopharyngeal otic ganglion supplies parotid salivary gland Vagus nerve many brs supply heart, pulmonary and GI tract as far as the midpoint of the colon
Описание слайда:
Parasympathetic Cranial Nerves Oculomotor nerve ciliary ganglion in orbit ciliary muscle & pupillary constrictor muscle inside eyeball Facial nerve pterygopalatine and submandibular ganglions supply tears, salivary & nasal secretions Glossopharyngeal otic ganglion supplies parotid salivary gland Vagus nerve many brs supply heart, pulmonary and GI tract as far as the midpoint of the colon

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Parasympathetic Sacral Nerve Fibers Form pelvic splanchnic nerves Preganglionic fibers end on terminal ganglia in walls of target organs Innervate smooth muscle and glands in colon, ureters, bladder & reproductive organs
Описание слайда:
Parasympathetic Sacral Nerve Fibers Form pelvic splanchnic nerves Preganglionic fibers end on terminal ganglia in walls of target organs Innervate smooth muscle and glands in colon, ureters, bladder & reproductive organs

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ANS Neurotransmitters Classified as either cholinergic or adrenergic neurons based upon the neurotransmitter released Adrenergic Cholinergic
Описание слайда:
ANS Neurotransmitters Classified as either cholinergic or adrenergic neurons based upon the neurotransmitter released Adrenergic Cholinergic

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Parasympathetic Cholinergic neurons release acetylcholine from preganglionic neurons & from parasympathetic postganglionic neurons Action: Excites or inhibits depending upon receptor type and organ involved Receptor: Nicotinic receptors are found on dendrites & cell bodies of autonomic NS cells and at NMJ Muscarinic receptors are found on plasma membranes of all parasympathetic effectors
Описание слайда:
Parasympathetic Cholinergic neurons release acetylcholine from preganglionic neurons & from parasympathetic postganglionic neurons Action: Excites or inhibits depending upon receptor type and organ involved Receptor: Nicotinic receptors are found on dendrites & cell bodies of autonomic NS cells and at NMJ Muscarinic receptors are found on plasma membranes of all parasympathetic effectors

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Sympathetic Adrenergic neurons release norepinephrine (NE) from postganglionic sympathetic neurons only Action: Excites or inhibits organs depending on receptors Receptor: Alpha1 and Beta1 receptors produce excitation Alpha2 and Beta2 receptors cause inhibition Beta3 receptors (brown fat) increase thermogenesis NE lingers at the synapse until enzymatically inactivated by monoamine oxidase (MAO) or catechol-O-methyltransferase (COMT)
Описание слайда:
Sympathetic Adrenergic neurons release norepinephrine (NE) from postganglionic sympathetic neurons only Action: Excites or inhibits organs depending on receptors Receptor: Alpha1 and Beta1 receptors produce excitation Alpha2 and Beta2 receptors cause inhibition Beta3 receptors (brown fat) increase thermogenesis NE lingers at the synapse until enzymatically inactivated by monoamine oxidase (MAO) or catechol-O-methyltransferase (COMT)

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Autonomic Nervous System Overview Anatomy Physiology Hypothalamus Sympathetic Parasympathetic
Описание слайда:
Autonomic Nervous System Overview Anatomy Physiology Hypothalamus Sympathetic Parasympathetic

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Physiological Effects of the ANS Some organs have only sympathetic innervation sweat glands, adrenal medulla, arrector pili mm & many blood vessels controlled by regulation of the “tone” of the sympathetic system Most body organs receive dual innervation innervation by both sympathetic & parasympathetic Hypothalamus regulates balance (tone) between sympathetic and parasympathetic activity levels
Описание слайда:
Physiological Effects of the ANS Some organs have only sympathetic innervation sweat glands, adrenal medulla, arrector pili mm & many blood vessels controlled by regulation of the “tone” of the sympathetic system Most body organs receive dual innervation innervation by both sympathetic & parasympathetic Hypothalamus regulates balance (tone) between sympathetic and parasympathetic activity levels

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Sympathetic Responses Dominance by the sympathetic system is caused by physical or emotional stress -- “E situations” emergency, embarrassment, excitement, exercise Alarm reaction = flight or fight response dilation of pupils increase of heart rate, force of contraction & BP decrease in blood flow to nonessential organs increase in blood flow to skeletal & cardiac muscle airways dilate & respiratory rate increases blood glucose level increase Long lasting due to lingering of NE in synaptic gap and release of norepinephrine by the adrenal gland
Описание слайда:
Sympathetic Responses Dominance by the sympathetic system is caused by physical or emotional stress -- “E situations” emergency, embarrassment, excitement, exercise Alarm reaction = flight or fight response dilation of pupils increase of heart rate, force of contraction & BP decrease in blood flow to nonessential organs increase in blood flow to skeletal & cardiac muscle airways dilate & respiratory rate increases blood glucose level increase Long lasting due to lingering of NE in synaptic gap and release of norepinephrine by the adrenal gland

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Parasympathetic Responses Enhance “rest-and-digest” activities Mechanisms that help conserve and restore body energy during times of rest Normally dominate over sympathetic impulses SLUDD type responses = salivation, lacrimation, urination, digestion & defecation 3 “decreases”--- decreased HR, diameter of airways and diameter of pupil Paradoxical fear when there is no escape route or no way to win causes massive activation of parasympathetic division loss of control over urination and defecation
Описание слайда:
Parasympathetic Responses Enhance “rest-and-digest” activities Mechanisms that help conserve and restore body energy during times of rest Normally dominate over sympathetic impulses SLUDD type responses = salivation, lacrimation, urination, digestion & defecation 3 “decreases”--- decreased HR, diameter of airways and diameter of pupil Paradoxical fear when there is no escape route or no way to win causes massive activation of parasympathetic division loss of control over urination and defecation

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Comparison
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Comparison

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Autonomic or Visceral Reflexes Autonomic reflexes occur over autonomic reflex arcs. Components of that reflex arc: sensory receptor sensory neuron integrating center pre & postganglionic motor neurons visceral effectors Unconscious sensations and responses changes in blood pressure, digestive functions etc filling & emptying of bladder or defecation
Описание слайда:
Autonomic or Visceral Reflexes Autonomic reflexes occur over autonomic reflex arcs. Components of that reflex arc: sensory receptor sensory neuron integrating center pre & postganglionic motor neurons visceral effectors Unconscious sensations and responses changes in blood pressure, digestive functions etc filling & emptying of bladder or defecation

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Control of Autonomic NS Not aware of autonomic responses because control center is in lower regions of the brain Hypothalamus is major control center input: emotions and visceral sensory information smell, taste, temperature, osmolarity of blood, etc output: to nuclei in brainstem and spinal cord posterior & lateral portions control sympathetic NS increase heart rate, inhibition GI tract, increase temperature anterior & medial portions control parasympathetic NS decrease in heart rate, lower blood pressure, increased GI tract secretion and mobility
Описание слайда:
Control of Autonomic NS Not aware of autonomic responses because control center is in lower regions of the brain Hypothalamus is major control center input: emotions and visceral sensory information smell, taste, temperature, osmolarity of blood, etc output: to nuclei in brainstem and spinal cord posterior & lateral portions control sympathetic NS increase heart rate, inhibition GI tract, increase temperature anterior & medial portions control parasympathetic NS decrease in heart rate, lower blood pressure, increased GI tract secretion and mobility

Слайд 29


Autonomic Dysreflexia Exaggerated response of sympathetic NS in cases of spinal cord injury above T6 Certain sensory impulses trigger mass stimulation of sympathetic nerves below the injury Result vasoconstriction which elevates blood pressure parasympathetic NS tries to compensate by slowing heart rate & dilating blood vessels above the injury pounding headaches, sweating warm skin above the injury and cool dry skin below can cause seizures, strokes & heart attacka
Описание слайда:
Autonomic Dysreflexia Exaggerated response of sympathetic NS in cases of spinal cord injury above T6 Certain sensory impulses trigger mass stimulation of sympathetic nerves below the injury Result vasoconstriction which elevates blood pressure parasympathetic NS tries to compensate by slowing heart rate & dilating blood vessels above the injury pounding headaches, sweating warm skin above the injury and cool dry skin below can cause seizures, strokes & heart attacka

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