🗊 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy

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Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №1 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №2 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №3 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №4 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №5 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №6 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №7 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №8 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №9 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №10 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №11 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №12 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №13 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №14 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №15 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №16 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №17 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №18 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №19 Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №20
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Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy
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Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy

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Overview  10700 y.a. – The betel nut was chewed in Thailand  7000 y.a. – Coca was being used in the Andes   Before European contact – Native Americans used tobacco
Описание слайда:
Overview  10700 y.a. – The betel nut was chewed in Thailand  7000 y.a. – Coca was being used in the Andes   Before European contact – Native Americans used tobacco

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Legality The resolution of the government of Russian Federation N 681 (30.06.1998) 1) list I: mescaline and its derivatives, hashish, heroin, marijuana, methadone, MMDA, opium, psilocybin , psilocin, ephedrine, etc. 2) list II: codeine, cocaine, morphine, ethylmorphine, omnopon, fentanyl, promedol, etc. 3) list III: barbital, nitrazepam, diazepam, taren, etc. 4) list IV:ephedrine, pseudoephedrine, acetone, sulphuric acid, hydrochloric acid, potassium permanganate, acetic acid, etc.
Описание слайда:
Legality The resolution of the government of Russian Federation N 681 (30.06.1998) 1) list I: mescaline and its derivatives, hashish, heroin, marijuana, methadone, MMDA, opium, psilocybin , psilocin, ephedrine, etc. 2) list II: codeine, cocaine, morphine, ethylmorphine, omnopon, fentanyl, promedol, etc. 3) list III: barbital, nitrazepam, diazepam, taren, etc. 4) list IV:ephedrine, pseudoephedrine, acetone, sulphuric acid, hydrochloric acid, potassium permanganate, acetic acid, etc.

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Mechanisms and effects Agonists: increasing the synthesis of one or more neurotransmitters reducing its reuptake from the synapses mimicking the action by binding directly to the postsynaptic receptor Antagonists: interfering with synthesis blocking postsynaptic receptors
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Mechanisms and effects Agonists: increasing the synthesis of one or more neurotransmitters reducing its reuptake from the synapses mimicking the action by binding directly to the postsynaptic receptor Antagonists: interfering with synthesis blocking postsynaptic receptors

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Mechanisms and effects
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Mechanisms and effects

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Psychoactive substances and drugs. Antidepressants Zvereva Mila school of pharmacy , слайд №6
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Addiction psychological dependence  physical dependence
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Addiction psychological dependence  physical dependence

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Usage Anxiolytics Example: Benzodiazepine Euphoriants Example: MDMA (Ecstasy), MDA, 6-APB, Indopan Stimulants ("uppers") Examples: amphetamine, caffeine, cocaine, nicotine Depressants ("downers"), including sedatives, hypnotics, and narcotics. Examples: ethanol (alcoholic beverages), opioids,  barbiturates,  benzodiazepines Hallucinogens, including  psychedelics, dissociatives and deliriants Examples: psilocybin, LSD, Salvia divinorum and nitrous oxide
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Usage Anxiolytics Example: Benzodiazepine Euphoriants Example: MDMA (Ecstasy), MDA, 6-APB, Indopan Stimulants ("uppers") Examples: amphetamine, caffeine, cocaine, nicotine Depressants ("downers"), including sedatives, hypnotics, and narcotics. Examples: ethanol (alcoholic beverages), opioids,  barbiturates,  benzodiazepines Hallucinogens, including  psychedelics, dissociatives and deliriants Examples: psilocybin, LSD, Salvia divinorum and nitrous oxide

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Ritual and spiritual
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Ritual and spiritual

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Recreation alcohol –in most areas of the world it is legal for those over a certain age tobacco – a legal drug cannabis caffeine - a legal drug, contained in coffee, tea, energy drinsks, and some soft drinks MDMA cocaine  amphetamines – prescribed for ADHD psilocybin mushrooms  LSD –banned in October 1968 by US President Lyndon B Johnson. opiates and opioids – available by prescription. tranquilizers – barbiturates, benzodiazepines - commonly prescribed for anxiety nitrous oxide - legal ketamine – used by paramedics in emergency situations for its  dissociative  and  analgesic qualities amyl nitrite – a vasodilator (legal) other drugs (antidepressants, tranquilizers, analgesics, etc)
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Recreation alcohol –in most areas of the world it is legal for those over a certain age tobacco – a legal drug cannabis caffeine - a legal drug, contained in coffee, tea, energy drinsks, and some soft drinks MDMA cocaine  amphetamines – prescribed for ADHD psilocybin mushrooms  LSD –banned in October 1968 by US President Lyndon B Johnson. opiates and opioids – available by prescription. tranquilizers – barbiturates, benzodiazepines - commonly prescribed for anxiety nitrous oxide - legal ketamine – used by paramedics in emergency situations for its  dissociative  and  analgesic qualities amyl nitrite – a vasodilator (legal) other drugs (antidepressants, tranquilizers, analgesics, etc)

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Pharmacoyherapy Anesthesia Pain management Mental disorders
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Pharmacoyherapy Anesthesia Pain management Mental disorders

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Depression and Antidepressants Key facts: Depression is a common mental disorder. Globally, more than 350 million people of all ages suffer from depression Depression is the leading cause of disability worldwide, and is a major contributor to the global burden of disease More women are affected by depression than men At its worst, depression can lead to suicide There are effective treatments for depression
Описание слайда:
Depression and Antidepressants Key facts: Depression is a common mental disorder. Globally, more than 350 million people of all ages suffer from depression Depression is the leading cause of disability worldwide, and is a major contributor to the global burden of disease More women are affected by depression than men At its worst, depression can lead to suicide There are effective treatments for depression

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Drugs used for the treatment of depression: Selective serotonin reuptake inhibitors (SSRIs) Serotonin/norepinephrine reuptake inhibitors (SNRIs) Atypical antidepressants Tricyclic antidepressants (TCAs) Monoamine oxidase inhibitors (MAOIs) St. John’s wort ( Hypericum perforatum)
Описание слайда:
Drugs used for the treatment of depression: Selective serotonin reuptake inhibitors (SSRIs) Serotonin/norepinephrine reuptake inhibitors (SNRIs) Atypical antidepressants Tricyclic antidepressants (TCAs) Monoamine oxidase inhibitors (MAOIs) St. John’s wort ( Hypericum perforatum)

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Selective serotonin reuptake inhibitors, SSRIs Citalopram (Celexa)  Escitalopram (Lexapro)  Fluoxetine (Prozac)  Paroxetine (Paxil)  Sertraline (Zoloft)  Vilazodone (Viibryd) Vortioxetine (Brintellix)
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Selective serotonin reuptake inhibitors, SSRIs Citalopram (Celexa)  Escitalopram (Lexapro)  Fluoxetine (Prozac)  Paroxetine (Paxil)  Sertraline (Zoloft)  Vilazodone (Viibryd) Vortioxetine (Brintellix)

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Serotonin/norepinephrine reuptake inhibitors, SNRIs Desvenlafaxine (Pristiq)  Duloxetine (Cymbalta) Venlafaxine (Effexor, Effexor XR) Levomilnacipran (Fetzima)
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Serotonin/norepinephrine reuptake inhibitors, SNRIs Desvenlafaxine (Pristiq)  Duloxetine (Cymbalta) Venlafaxine (Effexor, Effexor XR) Levomilnacipran (Fetzima)

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Other Antidepressants Bupropion (Wellbutrin) Mirtazapine (Remeron, Remeron SolTab) Trazodone (Desyrel, Oleptro)
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Other Antidepressants Bupropion (Wellbutrin) Mirtazapine (Remeron, Remeron SolTab) Trazodone (Desyrel, Oleptro)

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Tricyclic antidepressants, TCAs Amitriptyline (Elavil)  Desipramine (Norpramin)  Imipramine (Tofranil)  Clomipramine (Anafranil)  Nortriptyline (Pamelor)  Protriptyline (Vivactil) Doxepin (Sinequan, Silenor) Trimipramine (Surmontil)  Amoxapine  
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Tricyclic antidepressants, TCAs Amitriptyline (Elavil)  Desipramine (Norpramin)  Imipramine (Tofranil)  Clomipramine (Anafranil)  Nortriptyline (Pamelor)  Protriptyline (Vivactil) Doxepin (Sinequan, Silenor) Trimipramine (Surmontil)  Amoxapine  

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Monoamine oxidase inhibitors,MAO Is Selegiline transdermal patch (Emsam) Tranylcypromine (Parnate)  Phenelzine (Nardil)  Isocarboxazid (Marplan)
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Monoamine oxidase inhibitors,MAO Is Selegiline transdermal patch (Emsam) Tranylcypromine (Parnate)  Phenelzine (Nardil)  Isocarboxazid (Marplan)

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Herbals Hypericum perforatum (St John's Wort)
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Herbals Hypericum perforatum (St John's Wort)

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The End
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The End

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