Nano-enabled biological tissues - презентация, доклад, проект скачать

Нажмите для полного просмотра!

Nano-enabled biological tissues, слайд №1

Nano-enabled biological tissues, слайд №2

Nano-enabled biological tissues, слайд №3

Nano-enabled biological tissues, слайд №4

Nano-enabled biological tissues, слайд №5

Nano-enabled biological tissues, слайд №6

Nano-enabled biological tissues, слайд №7

Nano-enabled biological tissues, слайд №8

Nano-enabled biological tissues, слайд №9

Nano-enabled biological tissues, слайд №10

Nano-enabled biological tissues, слайд №11

Nano-enabled biological tissues, слайд №12

Nano-enabled biological tissues, слайд №13

Nano-enabled biological tissues, слайд №14

Nano-enabled biological tissues, слайд №15

Nano-enabled biological tissues, слайд №16

Nano-enabled biological tissues, слайд №17

Содержание ▲

Вы можете ознакомиться и скачать презентацию на тему Nano-enabled biological tissues. Доклад-сообщение содержит 17 слайдов. Презентации для любого класса можно скачать бесплатно. Если материал и наш сайт презентаций Mypresentation Вам понравились – поделитесь им с друзьями с помощью социальных кнопок и добавьте в закладки в своем браузере.

Слайды и текст этой презентации

Слайд 1

Описание слайда:

Nano-enabled Biological Tissues By Bradly Alicea Presented to PHY 913 (Nanotechnology and Nanosystems, Michigan State University). October, 2010.

Слайд 2

Описание слайда:

Nanoscale Technology Enables Complexity at Larger Scales…….

Слайд 3

Описание слайда:

Role of Scale (Size AND Organization)

Слайд 4

Описание слайда:

Ingredient I, Biomimetics/ Biocompatibility Biomimetics: engineering design that mimics natural systems. Nature has evolved things better than humans can design them. * can use biological materials (silks) or structures (synapses). Biocompatibility: materials that do not interfere with biological function. * compliant materials used to replace skin, connective tissues. * non-toxic polymers used to prevent inflammatory response in implants.

Слайд 5

Описание слайда:

Artificial Skin, Two Approaches

Слайд 6

Описание слайда:

Artificial Skin – Response Characteristics Results for stimulation of electronic skin: Output signal from electronic skin, representation is close to pressure stimulus. * only produces one class of sensory information (pressure, mechanical). Q: does artificial skin replicate neural coding? * patterned responses over time (rate-coding) may be possible. * need local spatial information (specific to an area a few sensors wide). * need for intelligent systems control theory at micro-, nano-scale.

Слайд 7

Описание слайда:

Silk as Substrate, Two Approaches

Слайд 8

Описание слайда:

Ingredient II, Flexible Electronics Q: how do we incorporate the need for compliance in a device that requires electrical functionality? * tissues need to bend, absorb externally-applied loads, conform to complex geometries, dissipate energy. A: Flexible electronics (flexible polymer as a substrate).

Слайд 9

Описание слайда:

E-skin for Applications Organic field effect transistors (OFETs): * use polymers with semiconducting properties. Thin-film Transistors (TFTs): * semiconducting, dielectric layers and contacts on non-Si substrate (e.g. LCD technology). * in flexible electronics, substrate is a compliant material (skeleton for electronic array).

Слайд 10

Описание слайда:

Ingredient III, Nanopatterning Q: how do we get cells in culture to form complex geometries?

Слайд 11

Описание слайда:

MWCNTs as Substrate for Neurons Multi-Wall CNT substrate for HC neurons: Nano Letters, 5(6), 1107-1110 (2005).

Слайд 12

Описание слайда:

Bottom-up vs. Top-down Approaches

Слайд 13

Описание слайда:

Top-down approach: Electrospinning Align nanofibers using electrostatic repulsion forces (review, see Biomedical Materials, 3, 034002 - 2008). Contact guidance theory: Cells tend to migrate along orientations associated with chemical, structural, mechanical properties of substrate.

Слайд 14

Описание слайда:

Bottom-up approach: Molecular Self-assembly Protein and peptide approaches commonly used. Protein approach – see review, Progress in Materials Science, 53, 1101–1241 (2008).

Слайд 15

Описание слайда:

Additional Tools: Memristor Memristor: information-processing device (memory + resistor, Si-based) at nanoscale. * conductance incrementally modified by controlling change, demonstrates short-term potentiation (biological synapse-like).

Слайд 16

Описание слайда:

Additional Tools: Bioprinting Bioprinting: inkjet printers can deposit layers on a substrate in patterned fashion. * 3D printers (rapid prototypers) can produce a complex geometry (see Ferrari, M., “BioMEMS and Biomedical Nanotechnology”, 2006).

Слайд 17

Описание слайда:

Conclusions Nano can play a fundamental role in the formation of artificial tissues, especially when considering: * emergent processes: in development, all tissues and organs emerge from a globe of stem cells. * merging the sensory (electrical) and biomechanical (material properties) aspects of a tissue. Advances in nanotechnology might also made within this problem domain. * scaffold design requires detailed, small-scale substrates (for mechanical support, nutrient delivery). * hybrid protein-carbon structures, or more exotic “biological” solutions (reaction-diffusion models, natural computing, Artificial Life)?