🗊 Презентация In vivo folding. In vitro folding: spontaneously

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In vivo folding. In vitro folding: spontaneously, слайд №1 In vivo folding. In vitro folding: spontaneously, слайд №2 In vivo folding. In vitro folding: spontaneously, слайд №3 In vivo folding. In vitro folding: spontaneously, слайд №4 In vivo folding. In vitro folding: spontaneously, слайд №5 In vivo folding. In vitro folding: spontaneously, слайд №6 In vivo folding. In vitro folding: spontaneously, слайд №7 In vivo folding. In vitro folding: spontaneously, слайд №8 In vivo folding. In vitro folding: spontaneously, слайд №9 In vivo folding. In vitro folding: spontaneously, слайд №10 In vivo folding. In vitro folding: spontaneously, слайд №11 In vivo folding. In vitro folding: spontaneously, слайд №12 In vivo folding. In vitro folding: spontaneously, слайд №13 In vivo folding. In vitro folding: spontaneously, слайд №14 In vivo folding. In vitro folding: spontaneously, слайд №15 In vivo folding. In vitro folding: spontaneously, слайд №16 In vivo folding. In vitro folding: spontaneously, слайд №17 In vivo folding. In vitro folding: spontaneously, слайд №18 In vivo folding. In vitro folding: spontaneously, слайд №19 In vivo folding. In vitro folding: spontaneously, слайд №20 In vivo folding. In vitro folding: spontaneously, слайд №21 In vivo folding. In vitro folding: spontaneously, слайд №22 In vivo folding. In vitro folding: spontaneously, слайд №23 In vivo folding. In vitro folding: spontaneously, слайд №24 In vivo folding. In vitro folding: spontaneously, слайд №25 In vivo folding. In vitro folding: spontaneously, слайд №26 In vivo folding. In vitro folding: spontaneously, слайд №27 In vivo folding. In vitro folding: spontaneously, слайд №28 In vivo folding. In vitro folding: spontaneously, слайд №29 In vivo folding. In vitro folding: spontaneously, слайд №30 In vivo folding. In vitro folding: spontaneously, слайд №31 In vivo folding. In vitro folding: spontaneously, слайд №32 In vivo folding. In vitro folding: spontaneously, слайд №33 In vivo folding. In vitro folding: spontaneously, слайд №34 In vivo folding. In vitro folding: spontaneously, слайд №35 In vivo folding. In vitro folding: spontaneously, слайд №36 In vivo folding. In vitro folding: spontaneously, слайд №37 In vivo folding. In vitro folding: spontaneously, слайд №38 In vivo folding. In vitro folding: spontaneously, слайд №39 In vivo folding. In vitro folding: spontaneously, слайд №40 In vivo folding. In vitro folding: spontaneously, слайд №41 In vivo folding. In vitro folding: spontaneously, слайд №42 In vivo folding. In vitro folding: spontaneously, слайд №43 In vivo folding. In vitro folding: spontaneously, слайд №44
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In vivo folding. In vitro folding: spontaneously, слайд №1
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In vivo folding. In vitro folding: spontaneously, слайд №2
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In vivo folding. In vitro folding: spontaneously, слайд №3
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In vivo folding. In vitro folding: spontaneously, слайд №4
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In vivo folding. In vitro folding: spontaneously, слайд №5
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In vivo folding. In vitro folding: spontaneously, слайд №6
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In vivo folding. In vitro folding: spontaneously, слайд №7
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In vivo folding. In vitro folding: spontaneously, слайд №8
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In vivo folding. In vitro folding: spontaneously, слайд №9
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In vivo folding. In vitro folding: spontaneously, слайд №10
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In vivo folding. In vitro folding: spontaneously, слайд №11
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In vivo folding. In vitro folding: spontaneously, слайд №12
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In vivo folding. In vitro folding: spontaneously, слайд №13
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In vivo folding. In vitro folding: spontaneously, слайд №14
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In vivo folding. In vitro folding: spontaneously, слайд №15
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PROTEIN PROTEIN FOLDING: current picture
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PROTEIN PROTEIN FOLDING: current picture

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In vivo folding. In vitro folding: spontaneously, слайд №17
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In vivo folding. In vitro folding: spontaneously, слайд №18
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In vivo folding. In vitro folding: spontaneously, слайд №19
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In vivo folding. In vitro folding: spontaneously, слайд №20
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In vivo folding. In vitro folding: spontaneously, слайд №21
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In vivo folding. In vitro folding: spontaneously, слайд №22
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In vivo folding. In vitro folding: spontaneously, слайд №23
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In vivo folding. In vitro folding: spontaneously, слайд №24
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In vivo folding. In vitro folding: spontaneously, слайд №25
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In vivo folding. In vitro folding: spontaneously, слайд №26
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In vivo folding. In vitro folding: spontaneously, слайд №27
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…any tilt of energy surface solves this “paradox”… (?) Zwanzig, 1992; Bicout & Szabo, 2000
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…any tilt of energy surface solves this “paradox”… (?) Zwanzig, 1992; Bicout & Szabo, 2000

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In vivo folding. In vitro folding: spontaneously, слайд №29
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Phillips (1965) hypothesis: Phillips (1965) hypothesis: folding nucleus is formed by the N-end of the nascent protein chain, and the remaining chain...
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Phillips (1965) hypothesis: Phillips (1965) hypothesis: folding nucleus is formed by the N-end of the nascent protein chain, and the remaining chain wraps around it. for single-domain proteins: NO: Goldenberg & Creighton, 1983: circular permutants: N-end has no special role in the in vitro folding.

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In vivo folding. In vitro folding: spontaneously, слайд №31
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In vivo folding. In vitro folding: spontaneously, слайд №32
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In vivo folding. In vitro folding: spontaneously, слайд №33
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In vivo folding. In vitro folding: spontaneously, слайд №34
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In vivo folding. In vitro folding: spontaneously, слайд №35
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In vivo folding. In vitro folding: spontaneously, слайд №36
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In vivo folding. In vitro folding: spontaneously, слайд №37
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In vivo folding. In vitro folding: spontaneously, слайд №38
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In vivo folding. In vitro folding: spontaneously, слайд №39
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In vivo folding. In vitro folding: spontaneously, слайд №40
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In vivo folding. In vitro folding: spontaneously, слайд №41
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In vivo folding. In vitro folding: spontaneously, слайд №42
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In vivo folding. In vitro folding: spontaneously, слайд №43
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In vivo folding. In vitro folding: spontaneously, слайд №44
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